%0 Journal Article %T Attention deficit hyperactivity disorder secondary to lesion of the basal ganglia %A Giovanni Mazzotta %A Lucia Lucia Cirulli %A Marco Sposato %A Domenico Serino %J World Journal of Neuroscience %P 44-46 %@ 2162-2019 %D 2012 %I Scientific Research Publishing %R 10.4236/wjns.2012.21007 %X Attention Deficit Hyperactivity Disorder (ADHD) is a childhood onset autoregulation disorder characterized by attention deficit, hyperactivity and/or impul- siveness, which results in social and academic functional impairment. ADHD has a complex aetiology: along with genetic factors, anomalies in several cere-bral districts have been reported. We describe the case of a 9 year old boy with glucose-6-phosphate dehydrogenase deficiency in association with memory, behavioural and attentive disabilities. The patient¡¯s clinical history is characterized by cerebral stroke at 3 years of age during a febrile episode, resulted in slight hemiparesis. Neuroimaging revealed a cystic lesion in the anterior portion of the right lenticular nucleus. Neuropsychological and psychiatric assess- ment evidenced alterations of executive functions. Diagnosis of ADHD secondary to lesion of the basal ganglia was made. We report the patient¡¯s clinical profile in the light of current evidence pointing towards dysfunction of the basal ganglia as a crucial aetiological factor in memory and executive function impairment. %K ADHD %K Basal Ganglia %K Attention Deficit %K Memory Deficit %K Stroke %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=17729