%0 Journal Article
%T Superf¨ªcie ocular e hepatite C
%A Gomes
%A Rachel Lopes Rodrigues
%A Marques
%A J¨²nia Cabral
%A Albers
%A Marcos Bottene Vila
%A Endo
%A Roberto Mitiaki
%A Dantas
%A Paulo Elias Correa
%A Felberg
%A S¨¦rgio
%J Arquivos Brasileiros de Oftalmologia
%D 2011
%I Conselho Brasileiro de Oftalmologia
%R 10.1590/S0004-27492011000200005
%X purpose: to evaluate the outcomes of the tests used for dry eye diagnosis in patients with hepatitis c virus, and to verify if there is any relationship between the duration of illness and intensity of ocular surface changes. methods: 25 patients with hepatitis c virus without treatment, and 29 patients with negative serologic tests for hepatitis c virus were selected. biomicroscopy, tear film crystallization test, tear film break-up time, evaluation of the corneal staining with 1% fluorescein sodium, schirmer i test, ocular surface staining with 1% rose bengal and esthesiometry were performed in both groups. results: in the schirmer i test, the group of patients with hepatitis c displayed lower values in both eyes (or p=0.0162; os p=0.0265). for the tear film break-up time, there was a lower score in the group with hepatitis c, but it was statistically significant only in the left eye (p=0.0007). regarding the ocular surface damage, the rose bengal staining test showed a higher average in the hepatitis group in both eyes (right p=0.0008; left p=0.0034). there was a difference in the average esthesiometry between the groups, being the average lower in infected patients (or p=0.0006; os p=0.0015). there was no linear association between time of hepatitis c infection and intensity observed in dry eye tests. conclusions: hepatitis c virus infection causes dry eye. further researches are necessary to establish the physiopathology and the relationship with sj£¿gren syndrome.
%K hepatitis c
%K dry eye syndromes
%K cornea
%K keratitis.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0004-27492011000200005&lng=en&nrm=iso&tlng=en