%0 Journal Article
%T Human immunodeficiency virus type- 1 subtypes of infected patients in Esp¨ªrito Santo, Brazil
%A Cabral
%A Val¨¦ria P
%A Cunha
%A Carla B
%A Magalhaes
%A Eneida FL
%A Pinto-Neto
%A Lauro F
%A Couto-Fernandez
%A Jos¨¦ Carlos
%A Dietze
%A Reynaldo
%A Morgado
%A Mariza G
%A Ribeiro-Rodrigues
%A Rodrigo
%J Mem¨®rias do Instituto Oswaldo Cruz
%D 2006
%I Instituto Oswaldo Cruz, Minist¨¦rio da Sa¨²de
%R 10.1590/S0074-02762006000800010
%X genetic variability of human immunodeficiency virus type - 1(hiv-1) is a potential threat for both diagnosis and treatment of hiv/aids, as well as the development of effective vaccines. up to now, hiv subtypes circulating among hiv-positive patients in the state of esp¨ªrito santo were not known. in the present study, blood samples from 100 therapy-na£¿ve hiv-1 infected patients were collected and the hiv subtype was determined through the heteroduplex mobility assay (hma). ninety-seven out of 100 studied samples were subtyped by hma, 73 samples (75.2%) were from subtype b, 9 (9.3%) from subtype f, 3 (3.1%) from subtype c, 6 (6.2%) benv/fgag, and another 6 (6.2%) fenv/bgag, what suggests that recombinant viruses were present in the studied samples. twenty-eight percent of the subtype b samples were represented by the brazilian b" subtype, which were identified by rflp with fok i. data presented here demonstrate that the epidemiological characteristics of the hiv epidemic in the state of esp¨ªrito santo are similar to those from the other southeastern states and helped to better understand the genetic polymorphism of hiv in brazil.
%K human immunodeficiency virus type 1 (hiv-1)
%K subtype
%K esp¨ªrito santo
%K brazil.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0074-02762006000800010&lng=en&nrm=iso&tlng=en