%0 Journal Article
%T Serological evidence of hantavirus infection in rural and urban regions in the state of Amazonas, Brazil
%A Gimaque
%A Jo£¿o Bosco Lima
%A Bastos
%A Michele de Souza
%A Braga
%A Wornei Silva Miranda
%A Oliveira
%A Cintia Mara Costa de
%A Castilho
%A M¨¢rcia da Costa
%A Figueiredo
%A Regina Maria Pinto de
%A Galusso
%A Elizabeth dos Santos
%A Itapirema
%A Evaulino Ferreira
%A Figueiredo
%A Luiz Tadeu Moraes de
%A Mour£¿o
%A Maria Paula Gomes
%J Mem¨®rias do Instituto Oswaldo Cruz
%D 2012
%I Instituto Oswaldo Cruz, Minist¨¦rio da Sa¨²de
%R 10.1590/S0074-02762012000100019
%X hantavirus disease is caused by the hantavirus, which is an rna virus belonging to the family bunyaviridae. hantavirus disease is an anthropozoonotic infection transmitted through the inhalation of aerosols from the excreta of hantavirus-infected rodents. in the county of itacoatiara in the state of amazonas (am), brazil, the first human cases of hantavirus pulmonary and cardiovascular syndrome were described in july 2004. these first cases were followed by two fatal cases, one in the municipality of mau¨¦s in 2005 and another in itacoatiara in 2007. in this study, we investigated the antibody levels to hantavirus in a population of 1,731 individuals from four different counties of am. sera were tested by igg/igm- enzyme-linked immune-sorbent assay using a recombinant nucleocapsid protein of the araraquara hantavirus as an antigen. ten sera were igg positive to hantavirus (0.6%). among the positive sera, 0.8% (1/122), 0.4% (1/256), 0.2% (1/556) and 0.9% (7/797) were from atalaia do norte, careiro castanho, itacoatiara and l¨¢brea, respectively. none of the sera in this survey were igm-positive. because these counties are distributed in different areas of am, we can assume that infected individuals are found throughout the entire state, which suggests that hantavirus disease could be a local emerging health problem.
%K hantavirus
%K igg antibodies to hantavirus
%K western brazilian amazon.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0074-02762012000100019&lng=en&nrm=iso&tlng=en