%0 Journal Article
%T Hydroxylation of a hederagenin derived saponin by a Xylareaceous fungus found in fruits of Sapindus saponaria
%A Murgu
%A Michael
%A Santos
%A Luiz F. Arruda
%A Souza
%A Gezimar D. de
%A Daolio
%A Cristina
%A Schneider
%A Bernd
%A Ferreira
%A Ant£¿nio Gilberto
%A Rodrigues-Filho
%A Edson
%J Journal of the Brazilian Chemical Society
%D 2008
%I Sociedade Brasileira de Qu¨ªmica, SBQ
%R 10.1590/S0103-50532008000500004
%X during our screening of tropical plants for endophyte microorganisms, a xylareaceous fungus was found living on the internal part of sapindus saponaria fruits. the fruits of s. saponaria accumulate great amounts of triterpenoidal and sesquiterpenoidal saponins. the saponin 3-o-(¦Â-d-xylopyranosyl)-(1¡ú3)-¦Á-l-rhamnopyranosyl-(1¡ú2)-¦Á-l-arabinopyranosyl-hederagenin was isolated using chromatographic methods, after alkaline hydrolysis of the crude extract obtained from s. saponaria fruits and added to the culture medium used to grows the fungus. a new saponin was isolated from this experiment by preparative scale hplc and characterized as a 22¦Á-hydroxy derivative. the structure of this hydroxylated saponin was elucidated based on interpretation of ms/ms data and nmr spectra.
%K sapindus saponaria
%K saponin
%K xylaria
%K biotransformation
%K hydroxylation.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-50532008000500004&lng=en&nrm=iso&tlng=en