%0 Journal Article
%T Isolation, X-ray crystal structure and theoretical calculations of the new compound 8-Eepicordatin and identification of others terpenes and steroids from the bark and leaves of Croton palanostigma Klotzsch
%A Brasil
%A Davi S. B.
%A M¨¹ller
%A Adolfo H.
%A Guilhon
%A Gisele M. S. P.
%A Alves
%A Cl¨¢udio N.
%A Peris
%A Gabriel
%A Llusar
%A Rosa
%A Moliner
%A Vicent
%J Journal of the Brazilian Chemical Society
%D 2010
%I Sociedade Brasileira de Qu¨ªmica, SBQ
%R 10.1590/S0103-50532010000400021
%X phytochemical studies of the bark and leaves of croton palanostigma klotzsch (euphorbiaceae) led to the isolation of a new clerodane diterpene, 8-epicordatin (2), in addition to 12-oxohardwickiic acid methyl ester (3), aparisthman, cordatin (1), ent-trachyloban-18-oic acid, ent-13-epimanoyl oxide, ent-3-oxo-13-epimanoyl oxide, ent-3¦Â-hydroxy-13-epimanoyl oxide, sitosterol, stigmasterol, stigmastan-3-one, 6¦Â-hydroxystigmast-4-en-3-one, 6¦Â-hydroxystigmasta-4,22-dien-3-one, stigmast-4-en-3-one, stigmasta-4,22-dien-3-one, 3-o-acetylaleuritolic acid, 11¦Á-hydroxyurs-12-en-3-one, ¦Á-amyrenone, 24-methylenecycloartenone and lupenone. these compounds were isolated using typical phytochemical procedures and the structures were deduced from spectroscopic studies, including 2d nmr experiments. in addition, the crystalline structure of 8-epicordatin (2) was determined by x-ray diffraction. nmr theoretical calculations at the b3pw91/dgdzvp level were used to confirm the assignment of the chemical shifts of the h-7¦Á and h-7¦Â hydrogens of 8-epicordatin.
%K croton palanostigma klotzsch
%K terpenes
%K steroids
%K nmr dft calculations
%K x-ray crystallography.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-50532010000400021&lng=en&nrm=iso&tlng=en