%0 Journal Article
%T As bases neurobiol¨®gicas do transtorno obsessivo-compulsivo e da s¨ªndrome de Tourette
%A Mercadante
%A Marcos T.
%A Rosario-Campos
%A Maria C.
%A Quarantini
%A Lucas C.
%A Sato
%A Fabio P.
%J Jornal de Pediatria
%D 2004
%I Sociedade Brasileira de Pediatria
%R 10.1590/S0021-75572004000300006
%X objective: to describe and discuss evidence-based articles on the neurobiology of obsessive-compulsive disorder and tourette syndrome. sources of data: a review of the most relevant papers on the phenomenology, neuroanatomy, neuroimaging, genetic and immunological aspects of these two disorders was performed. summary of the findings: ritualistic behaviors and repetitive thoughts have been extensively studied in the last years. the definitions of obsessive-compulsive disorder and tourette syndrome emphasize the existence of a continuum of symptoms, with high prevalence in the general population. neurobiological findings have implicated genetic and immunological factors in the etiology of these two disorders. conclusions: advances in neuroscience triggered genetic and immunological research studies, allowing new perspectives on the treatment of obsessive-compulsive disorder and tourette syndrome patients.
%K obsessive-compulsive disorder
%K tourette syndrome
%K tic disorders
%K neuroscience.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0021-75572004000300006&lng=en&nrm=iso&tlng=en