%0 Journal Article %T Triggering DTH and CTL Activity by fd Filamentous Bacteriophages: Role of CD4+ T Cells in Memory Responses %A Giovanna Del Pozzo %A Dina Mascolo %A Rossella Sartorius %A Alessandra Citro %A Pasquale Barba %A Luciana D'Apice %A Piergiuseppe De Berardinis %J Journal of Biomedicine and Biotechnology %D 2010 %I Hindawi Publishing Corporation %R 10.1155/2010/894971 %X The ability of fd bacteriophage particles to trigger different arms of the immune system has been previously shown by us with particular emphasis on the ability of phages to raise CTL responses in vitro and in vivo. Here we show that fd virions in the absence of adjuvants are able to evoke a DTH reaction mediated by antigen specific CD8 %U http://www.hindawi.com/journals/biomed/2010/894971/