%0 Journal Article
%T Management of Post-Mastectomy Radio-Necrotic Ulcers & Osteoradionecrosis
%A Alaadin Hussein
%A Rimoun Boutros
%A Amani Saber
%J Journal of Cancer Therapy
%P 433-441
%@ 2151-1942
%D 2019
%I Scientific Research Publishing
%R 10.4236/jct.2019.106036
%X <strong>Background</strong><span style=\"font-family:Verdana;\"><strong>:</strong> Breast cancer is still the most common indication for chest wall
irradiation, despite the advances in RTH techniques complications still occur,
and the time of its occurrence vary and could take few months to many years.
ORN usually manifests with pain, exposed bone, fistulae and pathological
fracture and the proper management needs proper debridement and coverage by
thick musc</span><span style=\"font-family:Verdana;\">u</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">locutaneous
flaps. </span><b><span style=\"font-family:Verdana;\">Objective: </span></b><span style=\"font-family:Verdana;\">To evaluate different techniques of surgical
management of post</span></span><span style=\"font-family:Verdana;\">-</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">irradiation
persistent radio-necrotic ulcer &amp; ORN with emphasis on the outcome of each
technique.</span><b><span style=\"font-family:Verdana;\"> Patients and methods:</span></b><span style=\"font-family:Verdana;\"> A retrospective study </span></span><span style=\"font-family:Verdana;\">from</span><span style=\"font-family:Verdana;\"> 2010</span><span style=\"font-family:Verdana;\"> to </span><span style=\"font-family:Verdana;\">2015 reviewed 20 patients
subjected to post-mastectomy radiotherapy as a treatment for breast cancer inNCICairo, and Minia oncology center Hospital,
Egypt. Cases were biopsied to exclude local recurrence. The age, sex, type of
ulcer, dose of radiotherapy received and the management done for these cases w</span><span style=\"font-family:Verdana;\">ere</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> recorded. </span><b><span style=\"font-family:Verdana;\">Results</span></b><span style=\"font-family:Verdana;\">:
Only 4 patients responded to conservative treatment in the form of repeated
dressings, and 16 patients needed surgical treatment; 5 of them were treated
with debridement and coverage with split thickness graft with high rate of
complications reaching 80%, the other 11 patients were reconstructed with musc</span></span><span style=\"font-family:Verdana;\">u</span><span style=\"font-family:Verdana;\">locutanoeus flaps, of
these 7 patients were reconstructed with LD flaps with 57.14% success rate and
minor complications only, the other 4 cases were reconstructed with TRAM flap
with 50% success and major loss of the flap in one case that needed salvage by
LD flap. Pre-operative comorbidity w</span><span
%K Radionecrotic Ulcer
%K Osteoradionecrosis
%K Pedicled Myo-Cutaneous Flaps
%K Breast Cancer
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=93100