%0 Journal Article
%T Infection of Wounds by Potential Bacterial Pathogens and Their Resistogram
%A Isyaka M. Tom
%A Muhammad M. Ibrahim
%A Askira M. Umoru
%A Jidda B. Umar
%A Musa A. Bukar
%A Ali B. Haruna
%A Abdullahi Aliyu
%J Open Access Library Journal
%V 6
%N 7
%P 1-13
%@ 2333-9721
%D 2019
%I Open Access Library
%R 10.4236/oalib.1105528
%X <div style="text-align:justify;">
	<span style="line-height:1.5;">The major innate barrier to the establishment of infections in internal tissues is the skin, the disruption of which leads to wound formation. Such wounds can be contaminated by bacterial pathogens thereby hampering the healing process and its management becomes resource demanding. Here, we assess the diversity of potential bacterial pathogens in the infection of different types of wounds among hospitalized patients. Three hundred and twenty wound swab samples were collected and processed via microscopy, and cultured on Blood, MacConkey and Chocolate Agar. Isolates were further confirmed</span><span style="line-height:1.5;"> using biochemical tests and Kirby Bauer disc diffusion test was used to determine their antimicrobial susceptibility pattern. 87.5% of samples collected yielded bacterial growth comprising of single bacterial isolates (52.17%) and polymicrobial/mixed growth (47.82%). Staphylococcus aureus (32.61%) was the most prevalent bacterial specie identified. Gram-negative bacteria (62.33%) were the most pervasive group, chief among which were E. coli (23.64%) and Pseudomonas aeruginosa (17.13%). Rate of infection was highest among Wound sepsis and Burns wound where Enterobacter spp. and Streptococcus spp. were the most prevalent respectively. Differences in wound type in relation to rate of infection with Gram-negative bacteria was statistically significant (f = 5.9592; df = 29; p-value = 0.001645; p &lt; 0.01; Mean ¡À SD = 7.633 ¡À 6.3706). Resistivity profile of isolates has shown that the most significant resistance rate was against Amoxicillin and Ampicillin, among Gram-positive and Gram-negative bacteria identified respectively. This suggests that wounds can be infected by potential bacterial pathogens which can exacerbate the progression of the wound and complicate the healing process.</span>
</div>
%K Wound
%K Infection
%K Bacterial Pathogens
%K Drug Resistance
%U http://www.oalib.com/paper/5391813