%0 Journal Article
%T MtsR, an Iron-Dependent Regulator in <i>Streptococcus iniae</i>
%A Jun Wang
%A Peng Wang
%A Yanyan Qin
%A Lili Zou
%J Agricultural Sciences
%P 609-618
%@ 2156-8561
%D 2018
%I Scientific Research Publishing
%R 10.4236/as.2018.95042
%X <em>Streptococcus iniae</em> (<em>S. iniae</em>) is a major pathogen that is capable of resulting severe economic loss to cultured fish. Steadily iron availability from micro-environment is an important virulence factor for pathogens, and <em>S. iniae</em> encodes the iron-transporter MtsABC to accomplish heme utilization, but very little was known about the mechanisms involved in regulating and maintaining iron balance in <em>S. iniae</em>. In this study, the role of a putative iron-dependent transcriptional regulator MtsR was investigated, and the results showed that MtsR regulated the expression of iron-transport mtsABC to control iron homeostasis in <em>S. iniae</em>.
%K &lt
%K i&gt
%K Streptococcus iniae&lt
%K /i&gt
%K Iron-Dependent Regulator
%K Iron Transporter
%K MtsR
%K MtsABC
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=85022