%0 Journal Article
%T Double-Lumen Needle Follicular Flushing System versus Single-Lumen Aspiration Needle in IVF/ICSI Patients with Poor Ovarian Response: A Meta-Analysis
%A Weijie Xing
%A Jianping Ou
%A Liuhong Cai
%A Xin Tao
%J Advances in Sexual Medicine
%P 167-178
%@ 2164-5205
%D 2017
%I Scientific Research Publishing
%R 10.4236/asm.2017.74014
%X <strong>Background: </strong>The present study performed a meta-analysis to comprehensively analyze existing randomized controlled trials (RCT) involving the use of double-lumen needle in patients with poor ovarian response to explore whether double-lumen needle was good for specific patients. <strong>Methods:</strong> The PubMed, EMBASE, Cochrane Library databases and two randomized controlled trials registration centers were thoroughly searched until April 2017. The clinical outcomes of IVF/ICSI cycles were compared between two groups with double-lumen needle and single-lumen needle. <strong>Results:</strong> Four RCT studies were included in this present meta-analysis. The oocytes yield was similar in two groups (OR 0.88, 95%CI 0.66 - 1.16; I<sup>2</sup> = 4%). The procedure time with double-lumen needle was significantly longer than that with single-lumen needle (IV = 1.98, 95%CI 0.95 - 3.00; I<sup>2</sup> = 86%). The fertilization rate with double-lumen needle was lower than that with single-lumen needle (OR 0.66, 95%CI 0.44 - 0.97; I<sup>2</sup> = 0%). There was no significant difference of live birth rate in two groups (OR 0.76, 95%CI 0.32 - 1.76; I<sup>2</sup> = 41%). <strong>Conclusion:</strong> Double-lumen needle could not benefit patients with a POR in terms of the number of oocytes retrieved, oocyte recovery rate, normal fertilization rate, clinical pregnancy rate, and live birth rate, compared with single-lumen needle.
%K Double-Lumen Needle
%K Single-Lumen Needle
%K Poor Ovarian Response
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=79675