%0 Journal Article %T Male Breast Cancer: Case Studies and Literature Review %A Zaied Sonia %A Khechine Wiem %A Abbess Ibtissem %A Amina Ben Salem %A Aloui Salma %A Bargaoui Hayfa %A Zoukar Olfa %A Mhabrech Houda %A Faleh Raja %A Laajili Hayet %A Daldoul Amira %J Open Access Library Journal %V 4 %N 7 %P 1-4 %@ 2333-9721 %D 2017 %I Open Access Library %R 10.4236/oalib.1103695 %X
Male breast cancer is a rare disease. In Tunisia, it represents 1% of all breast cancers and 1.6% of Male neoplasia. This work is a retrospective study about 5 male patients with breast cancer, treated in the department of medical oncology at Fattouma Bourguiba University Hospital of Monastir (Tunisia) during a period of 3 years from March 2013 to March 2016. Results showed that: invasive ductual carcinoma was the histological type found in all cases; the Her 2 neu was not overexpressed in all cases; hormone receptors were positive in all patients. Two patients had a locally advanced disease. Two patients were diagnosed with metastatic disease; pulmonary and bone metastases. Three patients who were diagnosed with no metastatic disease have had a mastectomy with Axillary lymph node dissection. Adjuvant chemotherapy was administered in two patients. Loco regional radiotherapy was performed in three patients. Tamoxifen-based hormone therapy was administered in three patients. Two patients were treated with palliative chemotherapy. One patient received two lines of chemotherapy with a global survival of 16 months, while the other received only one line of palliative chemotherapy with a global survival of 2 months. One patient received palliative hormone therapy type Tamoxifen with progression free survival of 7 months. Three patients who received curative treatments are in remission of their disease. To conclude male breast cancer is a rare disease with multiple and varied risk factors. It is similar in its clinical, histological and prognostic characteristics to breast cancer in women but also has different characteristics.
%K Breast neoplasms %K Male %K Diagnosis %K Treatment %K Prognosis %U http://www.oalib.com/paper/5287132