%0 Journal Article
%T Male Breast Cancer: Case Studies and Literature Review
%A Zaied Sonia
%A Khechine Wiem
%A Abbess Ibtissem
%A Amina Ben Salem
%A Aloui Salma
%A Bargaoui Hayfa
%A Zoukar Olfa
%A Mhabrech Houda
%A Faleh Raja
%A Laajili Hayet
%A Daldoul Amira
%J Open Access Library Journal
%V 4
%N 7
%P 1-4
%@ 2333-9721
%D 2017
%I Open Access Library
%R 10.4236/oalib.1103695
%X
Male breast cancer is a
rare disease. In Tunisia, it represents 1% of all breast cancers and 1.6% of
Male neoplasia. This work is a retrospective study about 5 male patients with
breast cancer, treated in the department of medical oncology at Fattouma
Bourguiba University Hospital of Monastir (Tunisia) during a period of 3 years
from March 2013 to March 2016. Results showed that: invasive ductual carcinoma was the histological
type found in all cases; the
Her 2 neu was not overexpressed in all cases; hormone receptors were positive in all patients.
Two patients had a locally advanced disease. Two patients were diagnosed with
metastatic disease; pulmonary and bone metastases. Three patients who were
diagnosed with no metastatic disease have had a mastectomy with Axillary lymph
node dissection. Adjuvant chemotherapy was administered in two patients. Loco
regional radiotherapy was performed in three patients. Tamoxifen-based hormone
therapy was administered in three patients. Two patients were treated with palliative
chemotherapy. One patient received two lines of chemotherapy with a global
survival of 16 months, while the other received only one line of palliative
chemotherapy with a global survival of 2 months. One patient received
palliative hormone therapy type Tamoxifen with progression free survival of 7
months. Three patients who received curative treatments are in remission of
their disease. To conclude male breast cancer is a rare disease with multiple
and varied risk factors. It is similar in its clinical, histological and
prognostic characteristics to breast cancer in women but also has different
characteristics.
%K Breast neoplasms
%K Male
%K Diagnosis
%K Treatment
%K Prognosis
%U http://www.oalib.com/paper/5287132