%0 Journal Article
%T Echocardiographic Measurement of Pulmonary Arterial Pressure in Patients with Sarcoidosis
%A Ipek Candemir
%A Ozlem Ozdemir Kumbasar
%J Open Journal of Respiratory Diseases
%P 7-13
%@ 2163-9418
%D 2016
%I Scientific Research Publishing
%R 10.4236/ojrd.2016.61002
%X Introduction: Pulmonary hypertension (PH) is a significant complication and is poor prognostic
factor for sarcoidosis. We evaluated various tests of diagnosis and treatment as well as the associations
between PH and value of six-minute walk test (6 MWT) in sarcoidosis patients. Methods:
This study was conducted with fifty patients with sarcoidosis. We grouped patients according to
echocardiography. Results: PH prevalence in sarcoidosis was found to be 10%. In cases with likely
PH, FEV1%, FVC%, MMF% was found to be lower. Although DLCO was less than 80% in the group
of likely PH and over 80% in the other, there were no statistical differences between two groups.
Mean value of FVC/DLCO ratio was 1.1 ¡À 0.38 in group of likely PH. There was no significant difference
between groups. Mean distance of 6 MWT was 464 ¡À 105 m in all cases. There were no statistical
differences between two groups in 6 MWT. Significant desaturation with exercise was observed
in cases with PH (p = 0.007). Conclusion: In all stages, patients who have longer disease
duration and abnormal pulmonary function tests, should be examined about PH. Patients should
undergo 6 MWT and presence of desaturation after 6 MWT, even without hypoxemia, should be
looked after and dealt with accordingly.
%K Sarcoidosis
%K PH
%K ECO
%K PFT
%K 6 MWT
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=63824