%0 Journal Article
%T Jacobsen/Paris-Trousseau Syndrome: Report of a Case with Emphasis on Platelet¡¯s Light Microscopic and Ultrastructure Findings
%A Michael Losos
%A Basil M. Kahwash
%A Miriam Conces
%A Joel Thompson
%A Riten Kumar
%A Samir B. Kahwash
%J Open Journal of Pathology
%P 8-13
%@ 2164-6783
%D 2016
%I Scientific Research Publishing
%R 10.4236/ojpathology.2016.61002
%X Jacobsen syndrome (JS) is a rare, inherited
disorder, characterized by facial and skull dysmorphism, mental retardation,
and platelet abnormalities. Paris-Trousseau syndrome (PTS) is a platelet
function disorder that may be encountered in patients affected by JS. PTS is
manifested by a mild lifelong bleeding tendency. Morphologically, the presence
of large fused platelet alpha granules is characteristic. We present a case of
Jacobsen syndrome in a child and highlight the typical morphologic and
ultrastructure findings of platelets.
%K Jacobsen Syndrome
%K Paris-Trousseau Syndrome
%K Platelet Microscopic Findings
%K Electron  Microscopy
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=62559