%0 Journal Article %T Fixation properties of subdivided populations with balancing selection %A Pierangelo Lombardo %A Andrea Gambassi %A Luca Dall'Asta %J Quantitative Biology %D 2014 %I arXiv %R 10.1103/PhysRevE.91.032130 %X In subdivided populations, migration acts together with selection and genetic drift and determines their evolution. Building up on a recently proposed method, which hinges on the emergence of a time scale separation between local and global dynamics, we study the fixation properties of subdivided populations in the presence of balancing selection. The approximation implied by the method is accurate when the effective selection strength is small and the number of subpopulations is large. In particular, it predicts a phase transition between species coexistence and biodiversity loss in the infinite-size limit and, in finite populations, a nonmonotonic dependence of the mean fixation time on the migration rate. In order to investigate the fixation properties of the subdivided population for stronger selection, we introduce an effective coarser description of the dynamics in terms of a voter model with intermediate states, which highlights the basic mechanisms driving the evolutionary process. %U http://arxiv.org/abs/1407.4656v2