%0 Journal Article %T Prevalence and Antibiotic Resistance Pattern of <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> in Urine Tract Infections at the La Paz Medical Center, Malabo, Equatorial Guinea %A Aleksey Shatalov %J Open Journal of Medical Microbiology %P 177-183 %@ 2165-3380 %D 2015 %I Scientific Research Publishing %R 10.4236/ojmm.2015.54022 %X The study was conducted to isolate and determine the antibiotic resistance in Escherichia coli and Klebsiella pneumonia from urine samples over a 2-year period (August 2013-September 2015) at the La Paz Medical Center, Malabo. A retrospective analysis of 785 urine culture samples over a 2-year period August 2013-September 2015 was carried out according to the routine protocol of urinalysis. Bacterial etiological agents were isolated from 155 (19.7%) samples with highest prevalence of Escherichia coli (55.5%) followed by Klebsiella pneumonia (23.2%), Proteus mirabilis (4.5%), Pseudomonas species (3.2%), Enterobacter species (2.6%), Enterococcus faecalis (2.6%) and others species (8.4%). The E. coli and K. pneumonia represent 78.7% of all isolated bacterial strains. The E. coli and K. pneumoniae isolates possess highly resistant to ampicillin, Trimethoprim/Sulfamethoxazole, Doxycycline, Amoxicicline/Clavulanic acid. Whereas K. pneumonia demonstrated also to be highly resistant to Gentamycin, Cefuroxime and Ceftriaxon, low level of resistance to Piperacilin/Tazobactam, Amikacin and the lowest to Imipenem. The alarming level of MDR strains to the first choice antibiotics treatment was observed. %K Urine Tract Infections %K Antibiotic Resistance %K < %K i> %K Klebsiella pneumonia< %K /i> %K < %K i> %K Escherichia coli< %K /i> %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=61500