%0 Journal Article %T Carbohydrate-Derived Organocatalysts for the Reduction of Imines with Trichlorosilane %A Xin Ge %A Chao Qian %A Xinzhi Chen %J Journal of Materials Science and Chemical Engineering %P 48-53 %@ 2327-6053 %D 2015 %I Scientific Research Publishing %R 10.4236/msce.2015.36008 %X

The backbone of D-glucosamine hydrochloride was fine-tuned and modified by protecting the hydroxyl groups. In order to reduce imines with trichlorosilane, the carbohydrate-derived organocatalysts were prepared and screened. Methyl-4,6-O-benzylidene-2-amino-2-deoxy-¦Á-D-glucopyr anoside was found as the best catalyst. The reduction was proceeded under CHCl3 as solvent at 40?C, affording 68% - 94% yield.

%K Carbohydrate %K Organocatalyst %K Reduction %K Imine %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=57703