%0 Journal Article
%T 新生儿先天性凝血因子VII缺乏一例报道<br>Neonatal Congenital Absence of Clotting Factor VII: A Case Report
%A 赵伟
%A 孙志群
%A 张立明
%A 尹延娥
%A 刘欣
%J Asian Case Reports in Pediatrics
%P 1-3
%@ 2328-0441
%D 2015
%I Hans Publishing
%R 10.12677/ACRP.2015.31001
%X <div style=\"text-align:justify;\">
	<span style=\"line-height:1.5;\">目的：探讨新生儿先天性凝血因子VII缺乏的原因和治疗方法。方法：对我科发现的1例新生儿先天性凝血因子VII缺乏病例进行临床资料的回顾性分析。结果：患儿因无明显原因及诱因发现皮肤出血点，转入新生儿重症监护室，经送检凝血因子VII：C 0.5%，提示凝血因子VII缺乏症，送检其父母、姐姐的凝血因子VII C分别为：28.5%、31.0%、和25.2%，提示与遗传因素有关。经反复输注凝血酶原复合物、新鲜冰冻血浆等治疗后，康复出院。结论：在临床工作中，新生儿存在凝血功能异常，治疗效果不满意，应及时完善凝血因子检查，以避免漏诊、误诊，延误病情。&lt;br/&gt;Objective: To investigate the causes and treatment of congenital absence of clotting factor VII. Me-thod: The clinical data of one infant with the disease of congenital absence of clotting factor VII in our department were retrospectively analyzed. Result: The infant was transferred to neonatal ICU because of the skin bleeding for no apparent reason. The determination of coagulation factor VII was C 0.5%, revealing the coagulation factor VII deficiency. The coagulation factor VII C of the in-fant’s parents and sister was respectively 28.5%, 31.0% and 25.2%, indicating the relationship with genetic factors. After repeated infusion of fresh frozen plasma and prothrombin complex, the infant recovered and was discharged from hospital. Conclusion: In clinical work, coagulant function abnormality of neonatal repeatedly, we should check the clotting factor as soon as possible in order to avoid missed diagnosis, misdiagnosis and delay treatment.</span><span style=\"line-height:1.5;\"></span>
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%K 新生儿，先天性凝血因子VII缺乏，新生儿出血症<br>Newborn
%K Coagulation Factor VII
%K Hemorrhagic Disease of Newborn
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=14792