%0 Journal Article
%T Neonatal Alloimmune Thrombocytopenia Due to Maternal Anti HPA1a Antibodies:  Case Report and Management of  Subsequent Pregnancy
%A Ver¨®nica Serrano-dela Cruz
%A Alicia Mart¨ªnez-Varea
%A Mar¨ªa Jos¨¦ N¨²£¿ez-Valera
%A Antonio Abad-Carrascosa
%A Vicente Diago
%A Alfredo Perales-Mar¨ªn
%J Open Journal of Obstetrics and Gynecology
%P 213-216
%@ 2160-8806
%D 2014
%I Scientific Research Publishing
%R 10.4236/ojog.2014.45035
%X <p class=\"MsoNormal\">
	<span lang=\"EN-US\" style=\"font-size:12pt;font-family:'}', serif;\"><span style=\"font-size:12px;font-family:Verdana;\">Fetoneonatal alloimmune
thrombocytopenia is an infrequent</span><span class=\"apple-converted-space\" style=\"font-size:12px;font-family:Verdana;\"> </span><span style=\"font-size:12px;font-family:Verdana;\">and
severe disease</span><span class=\"apple-converted-space\" style=\"font-size:12px;font-family:Verdana;\"> </span><span style=\"font-size:12px;font-family:Verdana;\">that is
unexpectedly found after an uncomplicated first pregnancy. Affected infants
might show unexplained purpura, intracranial hemorrhage, and/or
gastrointestinal or genitourinary hemorrhage.</span><span class=\"apple-converted-space\" style=\"font-size:12px;font-family:Verdana;\"> </span><span style=\"font-size:12px;font-family:Verdana;\">Nevertheless,
in asymptomatic newborns the thrombocytopenia may be discovered incidentally.
We describe a case report that highlights that the incidental diagnosis of FNAIT
allows both properly managing the newborn, and detecting maternal anti-HPA1a
antibodies in order to prevent the disease in subsequent pregnancies. A
non-invasive treatment based on IVIgG allowed to this patient to prevent FNAIT
in her second pregnancy.</span></span> 
</p>
%K Fetoneonatal Alloimmune Thrombocytopenia
%K Anti-HPA1a Antibodies
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=43942