%0 Journal Article
%T S100B and delirium in the geriatric acute care setting
%A Walaa W. Aly
%A Samia A. Abdul-Rahman
%A Salma M. S. El Said
%A Samah A. Bastawy
%J Advances in Aging Research
%P 1-5
%@ 2169-0502
%D 2014
%I Scientific Research Publishing
%R 10.4236/aar.2014.31001
%X <p>
	Delirium and its
relation to biochemical markers have been considered a study question in several research works. The relation between S100B
levels and delirium is still a matter of discussion. Objective: To compare the serum level of S100B in patients with
and without delirium and to detect the relation between S100B and delirium
subtypes. Method: A case control
study was conducted on 114 elderly (60 years and older) selected from the
geriatric acute care unit at Ain Shams University Hospitals. They were classified
into two groups; 58 elderly cases who had delirium diagnosed by Confusion
Assessment Method and 56 controls. Then delirium was reclassified according
to the subtypes of delirium into Hyperactive: 46 patients, hypoactive: 2 patients,
and Mixed: 10 patients. Serum S100B levels were determined by ELISA. Results: Cases were significantly
older than controls (72.4 ¡À 9.4 versus 66.9 ¡À 5.3 years respectively) (P &lt; 0.001).
S100B levels were higher in cases (32.4 ¡À 9.8 pg/ml) than controls (30 ¡À 9.3
pg/ml) but the difference was not
statistically significant (P = 0.19). There was no significant
difference in S100B levels between the different subtypes of delirium. Conclusion: Delirious patients had
higher S100B levels than controls but the difference was not statistically
significant.
</p>
%K Delirium
%K S100B
%K Elderly
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=42626