%0 Journal Article
%T Recyclable Cyclohexanediamine Derivatives as  Organocatalysts: Organocatalytic Reduction with  Trichlorosilane and Aldol Reaction
%A Yuya Tanimura
%A Kaori Ishimaru
%J International Journal of Organic Chemistry
%P 240-242
%@ 2161-4695
%D 2013
%I Scientific Research Publishing
%R 10.4236/ijoc.2013.34034
%X <p style=\"text-align:justify;\" class=\"MsoNormal\">
	<span style=\"font-family:Verdana;\" lang=\"X-NONE\">R</span><span style=\"font-family:Verdana;\" lang=\"EN-US\">eduction of ketimine with trichlorosilane was carried out using bisformamide catalyst</span><span lang=\"EN-US\"> </span><span style=\"font-family:Verdana;\" lang=\"EN-US\">1a</span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\"> derived from cyclohexanediamine to give the corresponding product in 81% yield with 39% ee. Deprotection of the formyl groups of the catalysts </span><span style=\"font-family:Verdana;\">1</span><span style=\"font-family:Verdana;\"> gave the corresponding diamines </span><span style=\"font-family:Verdana;\">2</span><span style=\"font-family:Verdana;\"> which were utilized in aldol reaction of acetone with 4-nitrobenzaldehyde. The reaction using </span><span style=\"font-family:Verdana;\">2b</span><span style=\"font-family:Verdana;\"> in brine afforded the aldol adduct in 81% yield with 29% ee.</span></span><span lang=\"EN-US\"><?xml:namespace prefix = o /><o:p></o:p></span> 
</p>
<p style=\"text-align:justify;\" class=\"MsoNormal\">
	<span style=\"font-family:Verdana;\" lang=\"EN-US\">&nbsp;</span> 
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%K Aldol Reaction
%K Cyclohexanediamine
%K Organocatalysis
%K Recyclable
%K Reduction
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=41366