%0 Journal Article
%T Piericidins, Novel Quorum-Sensing Inhibitors against Chromobacterium violaceum CV026, from Streptomyces sp. TOHO-Y209 and TOHO-O348
%A Kazuhiro Ooka
%A Atsushi Fukumoto
%A Tomoe Yamanaka
%A Kanako Shimada
%A Ryo Ishihara
%A Yojiro Anzai
%A Fumio Kato
%J Open Journal of Medicinal Chemistry
%P 93-99
%@ 2164-313X
%D 2013
%I Scientific Research Publishing
%R 10.4236/ojmc.2013.34012
%X Piericidin A1, 3กฏ-rhamnopiericidin A1, and a novel compound piericidin E, a new quorum-sensing (QS) inhibitor<br />
against Chromobacterium violaceum CV026, were isolated from the culture broth of Streptomyces sp. QS is well<br />
known as a microbial signaling system and controls certain types of gene expression resulting in bioluminescence,<br />
biofilm formation, swarming motility, antibiotic biosynthesis, and virulence factor production. C. violaceum CV026 is<br />
commonly used to determine qualitative and quantitative QS activity. The structures of piericidin derivatives were characterized,<br />
and their QS activities were determined.
%K Piericidin A1
%K 3กฏ-Rhamnopiericidin A1
%K Piericidin E
%K Quorum-Sensing Inhibitor
%K Chromobacterium violaceum CV026
%K N-Acylhomoserinlactone
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=40387