%0 Journal Article
%T A Case of Ectopic Growth Hormone Releasing  Hormone (GHRH) from Pancreatic  Neuroendocrine Tumor Resistant to Therapy
%A Ohoud Almohareb
%A Juan Rivera
%J Open Journal of Endocrine and Metabolic Diseases
%P 271-275
%@ 2165-7432
%D 2013
%I Scientific Research Publishing
%R 10.4236/ojemd.2013.37037
%X <p class=\"MsoNormal\" style=\"text-align:justify;\">
	<b><span lang=\"EN-US\" style=\"font-family:Verdana;\">Introduction: </span></b><span lang=\"EN-US\"><span style=\"font-family:Verdana;\">Ectopic
secretion of GHRH is a rare cause of acromegaly. However, its recognition is
clinically important because different therapeutic approaches are required. </span><b><span style=\"font-family:Verdana;\">Case
Presentation: </span></b><span style=\"font-family:Verdana;\">We present a challenging case of acromegaly secondary to
ectopic GHRH secretion from pancreatic neuroendocrine tumor in a 52</span></span><span lang=\"EN-US\" style=\"font-family:Verdana;\">-</span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\">year-old
female. The patient is treated with different modalities which include
pegvisomant in an attempt to control the stimulated GH-axis considering the
limited data about its use in treatment of ectopic acromegaly. </span><b><span style=\"font-family:Verdana;\">Conclusion: </span></b><span style=\"font-family:Verdana;\">GHRH-secreting
tumor is a rare cause of acromegaly. Surgical resection of the tumor is the
therapy of choice whenever possible. However, further studies are warranted for
unresectable tumor or resistant cases.</span></span><span lang=\"EN-US\"><o:p></o:p></span> 
</p>
<p class=\"MsoNormal\" style=\"text-align:justify;\">
	<span lang=\"EN-US\" style=\"font-family:Verdana;\"> </span> 
</p>
%K Ectopic GHRH
%K Acromegaly
%K Pancreatic Neuroendocrine Tumor
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=39672