%0 Journal Article
%T Efficacy of Hypertonic Saline and Normal Saline in the Treatment of Chronic Sinusitis
%A Ramabhadraiah Anil Kumar
%A Borlingegowda Viswanatha
%A Nisha Krishnamurthy
%A Niveditha Jayanna
%A Disha Ramesh Shetty
%J International Journal of Otolaryngology and Head & Neck Surgery
%P 90-96
%@ 2168-5460
%D 2013
%I Scientific Research Publishing
%R 10.4236/ijohns.2013.23022
%X <p class=\"MsoNormal\">
	<b><span lang=\"EN-US\" style=\"font-family:Verdana;\">Introduction</span></b><b><span lang=\"EN-US\" style=\"font-family:Verdana;\">: </span></b><span lang=\"EN-US\" style=\"font-family:Verdana;\">Chronic sinusitis affects all age groups
and is a cause for significant morbidity. Recent realization that noninfectious
inflammatory causes can predispose to infectious sinusitis has evoked renewed
interest in developing and documenting efficacious ancillary therapies that
could supplement antibiotic use. Hypertonic saline solution has been shown to
increase mucociliary clearance and ciliary beat frequency.</span><span lang=\"EN-US\"> </span><b><span lang=\"EN-US\" style=\"font-family:Verdana;\">Objectives</span></b><b><span lang=\"EN-US\" style=\"font-family:Verdana;\">: </span></b><span lang=\"EN-US\" style=\"font-family:Verdana;\">A double blinded randomized com</span><span lang=\"EN-US\" style=\"font-family:Verdana;\">parative study was
undertaken to evaluate the effect of hypertonic saline (3.5%) nasal drops and
normal saline (0.9%) nasal drops, to assess the tolerance of hypertonic saline
nasal drops and to know if hypertonic nasal drops improve the ¡°quality of life¡±
in patients with chronic sinusitis.</span><span lang=\"EN-US\"> </span><b><span lang=\"EN-US\" style=\"font-family:Verdana;\">Methods</span></b><b><span lang=\"EN-US\" style=\"font-family:Verdana;\">: </span></b><span lang=\"EN-US\" style=\"font-family:Verdana;\">Fifty patients diagnosed as chronic
sinusitis in the age group of 18</span><span lang=\"EN-US\" style=\"font-family:Verdana;\">-</span><span lang=\"EN-US\" style=\"font-family:Verdana;\">45 years were randomized into two groups; Group
A was treated with normal saline and Group B with 3.5% hypertonic saline for a
period of 4 weeks. Pre and Post treatment x</span><span lang=\"EN-US\" style=\"font-family:Verdana;\">-</span><span lang=\"EN-US\" style=\"font-family:Verdana;\">rays of the
paranasal sinuses (Water¡¯s view) were graded and radiological scores </span><span lang=\"EN-US\" style=\"font-family:Verdana;\">were </span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\">given
accordingly. The symptoms were evaluated before and after treatment using
visual analogue score. Patients were queried about tolerance to the nasal solution
and scores were given. </span><b><span style=\"font-family:Verdana;\">Conclu</span></b></span><b><span lang=\"EN-US\" style=\"font-family:Verdana;\">sion</span></b><b><span lang=\"EN-US\" style=\"font-family:Verdana;\">:</span></b><span lang=\"EN-US\"> </span><span
%K Chronic Sinusitis
%K Hypertonic Saline
%K Normal Saline
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=31845