%0 Journal Article
%T Separation of Enantiomers of Clopidogrel on Chiral Stationary Phases by Packed Column Supercritical Fluid Chromatography
%A Khagga Bhavyasri
%A D. Rambabu
%A P. S. S. Prasad
%A V. Murali Balaram
%J American Journal of Analytical Chemistry
%P 51-55
%@ 2156-8278
%D 2013
%I Scientific Research Publishing
%R 10.4236/ajac.2013.41007
%X <p>
	<span><span style=\"font-family:Verdana;\">A packed column supercritical fluid chromatography (SFC) method for the
separation of clopidogrel enantiomers on a chiral stationary phase and CO</span><sub><span style=\"font-family:Verdana;\">2</span></sub><span style=\"font-family:Verdana;\"> with modifier as mobile phase has been developed at an analytical scale. Among
11 different 2 stationary phases the Chiral cel OD-H column showed by far the
best separation properties. The influence of different modifiers, injection
solvents, temperature, and pressure, and density of the fluid, respectively, on
the separa</span></span><span style=\"font-family:Verdana;\">tion behaviour
has been studied. It was found that the separation behaviour strongly depends
on the type of modifier and the modifier content. Temperature and pressure are
of less influence.</span> 
</p>
%K Chiral Stationary Phases
%K SFC
%K Enantiomer Separation
%K Supercritical Fluid Chromatography
%K Clopidogrel
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=26969