%0 Journal Article
%T Seroepidemiology of hepatitis A virus in Hyderabad, South India
%A Rahamathulla Syed
%A Aejaz Habeeb Mohammed
%A Prathap Kumar Sindiri
%A Arif Aziz Nathani
%J Journal of Medical and Allied Sciences
%D 2012
%I Deccan College of Medical Sciences
%X The present study was carried to determine the prevalence of Hepatitis A virus (HAV) IgM antibody among general population in Hyderabad since January 2002 to December 2011. A total of 4571 subjects were selected and divided into groups on the basis of age. The serum samples were screened for the presence of HAV IgM antibodies (anti-HAV IgM) using a commercially available enzyme linked immunosorbent assay (ELISA) kit. Of the 4571 serum samples, 4257 were negative and 314 (6.87%) were positive for the HAV IgM assay. The disease predominance was more in males (212) with 67.51% compared to females (102) with 32.48%. Anti-HAV seroprevalence was measured for the following age groups: Early (¡Ü20 years), Middle (21-40 years) and Late (¡Ý41 years). Average age-wise IgM-anti-HAV positivity from 2002-2011 was 234 of 314 in ¡Ü20 years, 74.52%), 73 of 314 (21-40 years, 23.24%), and 7 of 314 (¡Ý41 years, 2.22%). The present study will provide insights to the recent epidemiologic features of HAV infection in South India.
%K HAV
%K ELISA
%K epidemiology
%U http://www.jmas.in/Vol2Issue2/Seroepidemiology%20of%20hepatitis%20A%20virus%20in%20Hyderabad,%20South%20India.pdf