%0 Journal Article
%T Colonoscopy-based diagnosis of portal hypertensive colopathy in cirrhotic patients and relation to hepatic disease pathogenesis
%A CHEN Linyan
%J Journal of Clinical Hepatology
%D 2013
%I Journal of Clinical Hepatology
%X ObjectiveTo evaluate the rate of colonoscopy-based diagnosis of portal hypertensive colopathy (PHC) in patients with cirrhosis and evaluate associations with the hepatic disease pathogenic features. MethodsTwenty-three cirrhotic patients who underwent colonoscopy between January 2009 and May 2012 were enrolled in the study. The colonoscopy examination results, Child-Pugh scores, esophageal varices stages, and aspartate aminotransferase to platelet ratio index (APRI) values were recorded for each patient. The significance of inter-group differences was assessed by Chi-squared test or Fisher¡äs exact test. ResultsThe most common colonoscopy finding was PHC (9/23, 39.1%). Only 8.7% (2/23) of patients had completely normal findings. Occurrence of PHC was associated with moderate to severe esophageal varices (P=0.086) but not with severe liver fibrosis, either by APRI index or Child-Pugh score. ConclusionThe majority of cirrhosis patients had anomalous colonoscopy findings, and more than one-third had PHC. Colonoscopy should be considered for cirrhotic patients to identify previously undiagnosed PHC and initiate timely treatment.
%K colonoscopes
%K liver cirrhosis
%K esophageal and gastric varices
%K hypertension
%K portal
%U http://www.lcgdbzz.org/qk_content.asp?id=5347&ClassID=5416634