%0 Journal Article %T SYNTHESIS AND ANTIMICROBIAL EVALUATION OF CHROMONES BEARING 1, 5-BENZO THIAZEPINYL MOIETY %A R.V. Dengle* and R. N. Deshmukh %J International Journal of Pharmaceutical Sciences and Research %D 2013 %I Society of Pharmaceutical Sciences and Research %X ABSTRACT: 1, 5-Benzothazepinyl chromones were synthesized starting from 2, 4-diacyl phenol. The 2, 4-diacyl phenol was condensed with aryl aldehydes to obtain bis-chalcones1a-d. The bis-chalcones on cyclocondensation with equimolar amount of 2-aminothiophenol gave 1, 5-benzothiazepinyl chalcones2a-d. The chalcones on oxidative cyclisation in DMSO - I2 yielded the titled compounds3a-d. The microbial evaluation of the representative 1, 5-benzothiazepinyl chromones has also been performed. %K 1 %K 5-Benzothiazepines %K Antimicrobial %K Chromones %K Bischalcone %U http://www.ijpsr.com/V4I4/35%20Vol.%204,%20Issue%204,%20IJPSR,%20April%202013,%20RA-%202254,%20Paper%2035.pdf