%0 Journal Article
%T Phytochemistry and Pharmacological Activities of Silybum marianum: A Review
%A Tekeshwar Kumar
%A Yogesh Kumar Larokar
%A Shiv Kumar Iyer
%A Arvind Kumar
%J International Journal of Pharmaceutical and Phytopharmacological Research
%D 2012
%I International Journal of Pharmaceutical and Phytopharmacological Research
%X Silybum marianum (Milk thistle), a member of the Asteraceae family, is a tall herb with large prickly whiteveined green leaves and a reddish-purple  ower that ends in sharp spines. Certain phytoconstituents were revealed such as silybin A, silybin B, isosilybin A, isosilybin B, silychristin, silydianin, apigenin 7-O-¦Â-(2¡å-O-¦Á-rhamnosyl)galacturonide, kaempferol 3-O-¦Á-rhamnoside-7-O-¦Â-galacturonide, apigenin 7-O-¦Â-glucuronide, apigenin 7-O-¦Â-glucoside, apigenin 7-O-¦Â-galactoside, kaempferol-3-O-¦Á-rhamnoside, kaempferol, taxifolin and quercetin. The plant is exclusively used as anti-diabetic, hepatoprotective,hypocholesterolaemic, anti-hypertensive, anti-inflammatory, anti-cancer, and as an anti-oxidant. Seeds of the plant are also used as an anti-spasmodic, neuroprotective, anti-viral, immunomodulant, cardioprotective, demulcent and anti-haemorrhagic. The plant is also serves as a galactagogue and used in the treatment of uterine disorders. This review paper focuses mainly on phytochemistry and pharmacological activities of the legendary plant milk thistle.
%K Silybum marianum
%K Silybin
%K Silychristin
%K Phytochemistry
%K Anti-diabetic
%K Hepatoprotective
%U http://www.eijppr.com/jan-2012/8.pdf