%0 Journal Article
%T Piper nigrum, Piper betle and Gnetum gnemon- Natural Food Sourcewith Anti-Quorum Sensing Properties
%A Li Ying Tan
%A Wai-Fong Yin
%A Kok-Gan Chan
%J Sensors
%D 2013
%I MDPI AG
%R 10.3390/s130303975
%X Various parts of Piper nigrum, Piper betle and Gnetum gnemon are used as food sources by Malaysians. The purpose of this study is to examine the anti-quorum sensing (anti-QS) properties of P. nigrum, P. betle and G. gnemon extracts. The hexane, chloroform and methanol extracts of these plants were assessed in bioassays involving Pseudomonas aeruginosa PA01, Escherichia coli [pSB401], E. coli [pSB1075] and Chromobacterium violaceum CV026. It was found that the extracts of these three plants have anti-QS ability. Interestingly, the hexane, chloroform and methanol extracts from P. betle showed the most potent anti-QS activity as judged by the bioassays. Since there is a variety of plants that serve as food sources in Malaysia that have yet to be tested for anti-QS activity, future work should focus on identification of these plants and isolation of the anti-QS compounds.
%K natural products
%K Pseudomonas aeruginosa
%K pathogenicity
%K pyocyanin
%K quorum sensing
%K quorum quenching
%K swarming
%K violacein
%K virulence
%U http://www.mdpi.com/1424-8220/13/3/3975