%0 Journal Article
%T Anti-M: Report of two cases and review of literature
%A Tondon Rashmi
%A Kataria Rahul
%A Chaudhry Rajendra
%J Asian Journal of Transfusion Science
%D 2008
%I Medknow Publications
%X Anti-M is a fairly common naturally occurring antibody with rarely causing hemolytic transfusion reactions or hemolytic disease of the newborn. Most anti-M are not active at 37 o C and can generally be ignored in transfusion practice. However, we did not find this antibody to be fairly common and detected only two cases of anti-M in the past three years. We describe these two cases; one ¡äimmunizing¡ä type and other ¡änaturally occurring¡ä and review the literature. The immunizing type was reactive at 37 o C as well as AHG phase of testing with IgG component, and showing dosage effect while the other was ¡änaturally occurring¡ä reactive well below 37 o C. Though rare, sometimes these antibodies can be of clinical significance when the antibody detected is reactive at 37 o C and AHG phase. When the antibody is active at 37 o C, M antigen negative cross match compatible red cell unit should be given.
%K Anti-M
%K immunizing
%K naturally occurring
%U http://www.ajts.org/article.asp?issn=0973-6247;year=2008;volume=2;issue=2;spage=81;epage=83;aulast=Tondon