%0 Journal Article %T Genetic predictors of idiopathic sick sinus syndrome %A A. A. Chernova %A S. Yu. Nikulina %A S. S. Tret'yakova %J Rational Pharmacotherapy in Cardiology %D 2012 %I Rational Pharmacotherapy in Cardiology %X Published data demonstrating genetic determination of sick sinus syndrome is presented. The definition of this pathology is presented; the main symptoms are described, as well as genes that influence the development of idiopathic sick sinus syndrome, their polymorphisms and role in disorders of the cardiovascular system. %K idiopathic sinus syndrome %K genetic determinism %K myosin heavy chains (MYH6) gene %K SCN5A %K HCN4 %K konneksin-40 %K ADRA2B gene %K endothelial NO-synthase gene %U http://www.rpcardio.com/archive/article.php?ID=3766