%0 Journal Article %T Long term combination treatment for severe idiopathic pulmonary arterial hypertension %A Flora Affuso %A Plinio Cirillo %A Antonio Ruvolo %A Guido Carlomagno %J World Journal of Cardiology %D 2010 %I Baishideng Publishing Group Co. Limited %X We report the long-term follow-up of 3 cases of severe idiopathic pulmonary arterial hypertension, in whom tadalafil plus sitaxentan combination therapy improved the clinical condition and exercise performance without any relevant adverse event. %K Pulmonary hypertension %K Tadalafil %K Sitaxentan %K Endothelin receptors %U http://www.wjgnet.com/1949-8462/full/v2/i3/68.htm