%0 Journal Article
%T A case of focal segmental glomerulosclerosis in an adult patient with hypogammaglobulinemia superimposed on membranoproliferative glomerulonephritis in childhood
%A Kenji Tsuji
%A Haruhito A Uchida
%A Tetsuichiro Ono
%A Tasuyuki Inoue
%A Katsuji Shinagawa
%A Shinji Kitamura
%A Yohei Maeshima
%A Hitoshi Sugiyama
%A Hirofumi Makino
%J BMC Nephrology
%D 2012
%I BioMed Central
%R 10.1186/1471-2369-13-46
%X We report a 36-year-old man who had suffered membranoproliferative glomerulonephritis (MPGN) in his childhood, later diagnosed with CVID at 35£¿years of age. He presented at our hospital with signs of proteinuria. A renal biopsy revealed he suffered from focal segmental glomerulosclerosis (FSGS), possibly due to obesity and hypertension, not CVID - associated MPGN.This is the first case report of FSGS in a CVID patient. In this case, we have to pay attention not only to the treatment of obesity and hypertension for FSGS but also to the recurrence of immune-complex glomerulonephritis such as MPGN, in case of the restoration of hypogammaglobulinemia.
%K Hypogammaglobulinemia
%K Focal segmental glomerulosclerosis
%K Proteinuria
%U http://www.biomedcentral.com/1471-2369/13/46/abstract