%0 Journal Article %T Is a Pacific Coexistence Between Virus and Host the Unexploited Path That May Lead to an HIV Functional Cure? %A Jonathan Fior %J Viruses %D 2013 %I MDPI AG %R 10.3390/v5020753 %X The SupT1 cell line supports optimal HIV-1 replication, and prolonged in vitro replication in SupT1 cells renders the virus significantly less virulent. This raises the question of whether the infusion of SupT1 cells could be used as a cell-based therapy to induce a pacific coexistence between the HIV virus and its human host. In a recent study, I investigated this potential therapeutic strategy in vitro. The results suggested that this approach should be further explored in HIV-susceptible animal models. Such studies may lead to the development of a functional cure for HIV infection. %K HIV infection %K Functional cure %K Cell-based therapy %K Vif %K APOBEC3G %K SupT1 cells %K HIV reservoir %K CD4+ T cells %U http://www.mdpi.com/1999-4915/5/2/753