%0 Journal Article %T An Indian perspective on primary angle closure and glaucoma %A Sihota Ramanjit %J Indian Journal of Ophthalmology %D 2011 %I Medknow Publications %X Aim: To provide a synopsis of primary angle closure disease in India, and Indian studies on the same. Results: Primary angle closure glaucoma forms almost half of all adult primary glaucomas seen in a hospital setting in India. Anatomically, corneal diameters and anterior chamber depths were least in acute and chronic PACG eyes as compared to subacute eyes and controls. Besides relative pupillary block, a Valsalva maneuver during activities of daily living may be responsible for intermittent angle closure and raised IOP in predisposed eyes. Iridotomy alone, controlled the intraocular pressure in 66.7% of subacute eyes and 12.9% of the acute. Medical therapy was additionally required for 35.5% of the acute eyes, 12.1% of the subacute and 30.0% of the chronic cases. There was a greater mean and peak IOP reduction, achieved with 0.005% latanoprost once daily, 8.2 ¡À 2.0 mm Hg, compared with 0.5% timolol twice daily, 6.1 ¡À 1.7 mm Hg2. A progression of PACS to PAC was seen in 22%, PAC to PAC OHT in 38.7% and PAC OHT to PACG in 30.7% over 5 years. Conclusions: Primary angle closure disease is common in India, and can be managed well with iridotomy, followed by an appropriate control of IOP. %K Primary angle closure %K glaucoma %K India %K primary angle closure glaucoma %K primary angle closure disease %U http://www.ijo.in/article.asp?issn=0301-4738;year=2011;volume=59;issue=7;spage=76;epage=81;aulast=Sihota