%0 Journal Article %T Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities %A Higuchi Maria de Lourdes %J Mem¨®rias do Instituto Oswaldo Cruz %D 1999 %I Instituto Oswaldo Cruz, Minist¨¦rio da Sa¨²de %X This article tries to demonstrate by new pathological findings (with the use of immunohistochemical technique and confocal laser microscopy) that chronic chagasic cardiomyopathy is a result of multiple factors involving myocarditis, immunodepression, severe fibrosis and microvessels dilatation and that all of these alterations are probably directly related with the presence of Trypanosoma cruzi parasites in the host associated with inadequate immunological response of the host. %K Chagas disease %K myocarditis %K Trypanosoma cruzi %K immunodepression %U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700044