%0 Journal Article %T Toxic epidermal necrolysis and agranulocytosis: Rare adverse effects of ciprofloxacin %A Upadya Gatha %A Ruxana K %J Indian Journal of Medical Sciences %D 2009 %I Medknow Publications %X Ciprofloxacin is one of the most commonly used antibacterial agents with relatively few side effects. Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0.6%. Recently we came across two rare adverse effects of ciprofloxacin, viz. toxic epidermal necrolysis and agranulocytosis. To our knowledge, a total of seven cases have been reported in the literature documenting an association between oral ciprofloxacin administration and toxic epidermal necrolysis. One case of granulocytopenia, four of pancytopenia and fifteen of leucopenia worldwide have been reported. With the use of ciprofloxacin becoming more and more widespread, these two rare but fatal complications of ciprofloxacin should be borne in mind. %K Adverse drug effects %K agranulocytosis %K ciprofloxacin %K toxic epidermal necrolysis %U http://www.indianjmedsci.org/article.asp?issn=0019-5359;year=2009;volume=63;issue=10;spage=461;epage=463;aulast=Upadya