%0 Journal Article %T SEROLOGIC DYNAMIC OF INFECTIO US BRONCHITIS VIRUS IN A BROILER FLOCK IN CUNDINAMARCA DIN¨¢MICA SEROL¨®GICA DEL VIRUS DE BRONQUITIS INFECCIOSA EN UNA GRANJA DE POLLO DE ENGORDE DEL DEPARTAMENTO DE CUNDINAMARCA %A Alvarez Espejo Diana Claudia %A Usma Jorge Alberto %A Jaime Correa Jairo %A Vera Alfonso Victor Julio %J Revista de la Facultad de Medicina Veterinaria y de Zootecnia %D 2009 %I Universidad Nacional de Colombia %X The infectious bronchitis virus (IBV) causes a highly contagious disease, spread worldwide, leading to serious economic losses. Sometimes the disease is associated with other entities such as infectious bursal disease virus, Newcastle disease virus, Mycoplasma gallisepticum and Escherichia coli. The highly genetic variability of the virus has generated a large number of viral strains with different clinical presentations. The objective was to assess the dynamics of the virus antibodies in birds vaccinated and not vaccinated against IBV, hosted on a broiler farm where the agent was detected by RT-PCR in Fusagasuga, Colombia and vaccinated birds in semi-isolation conditions in Bogot¨¢. To order this, 3 groups of birds (Ross 308) from 1 day of age (44 birds/group), which were vaccinated with a live attenuated virus strain Massachusetts H120, and the immune response was evaluated through the Elisa test. Since day 24 of age the birds showed a progressive decrease in antibody titers in all three groups, although in the vaccinated and unvaccinated birds kept at the farm were found higher levels of antibodies in the group of semi-isolation. Starting at day 28 in the birds housed in field, the antibodies titles rose slightly until the end of cycle. The slight increase in the level of antibodies may result from exposure to the virus vaccine generated a reversal of pathogenic viral persistence or a late exposure to field virus. El virus de bronquitis infecciosa (IBV) causa una enfermedad altamente contagiosa, distribuida mundialmente, que conlleva graves p¨¦rdidas econ¨®micas. En algunas oportunidades se asocia con otras entidades como los virus de las enfermedades de Gumboro y de Newcastle, Mycoplasma gallisepticum y Escherichia coli. La alta variabilidad gen¨¦tica del virus ha generado una gran cantidad de cepas virales con diferentes cuadros cl¨ªnicos. El objetivo del trabajo fue evaluar la din¨¢mica de anticuerpos del IBV en aves vacunadas y no vacunadas contra IBV, alojadas en una explotaci¨®n de pollo de engorde donde se detect¨® el agente por RT-PCR, en Fusagasug¨¢, Colombia, y aves vacunadas en semiaislamiento en Bogot¨¢. Para esto se organizaron 3 grupos de aves (Ross 308) de 1 d¨ªa de edad (44 aves/grupo), las cuales fueron vacunadas con un virus vivo atenuado, cepa Massachusetts H120, y se evalu¨® la respuesta inmune a trav¨¦s de la prueba de Elisa. Desde el primer d¨ªa hasta el d¨ªa 24 de edad se observ¨® una disminuci¨®n progresiva de los t¨ªtulos de anticuerpos en los tres grupos, aunque en las aves vacunadas y no vacunadas mantenidas en granja se observaron niveles d %K Cundinamarca %K IBV %K prueba de Elisa %K serolog¨ªa. %U http://www.revistas.unal.edu.co/index.php/remevez/article/view/13391