%0 Journal Article %T Methotrexate induced lung injury in a patient with primary CNS lymphoma : A case report %A puneet chhabra %A arjun dutt law %A dr vikas suri %A dr pankaj malhotra %J Mediterranean Journal of Hematology and Infectious Diseases %D 2012 %I %R 10.4084/mjhid.2012. %X Methotrexate is an antimetabolite commonly used in clinical practice for a variety of indications ranging from rheumatoid arthritis and other connective tissue disorders to high dose regimens in many malignancies. This folate antagonist has got a spectrum of toxicities among which gastrointestinal effects predominate . Lung injury is a well described but rare event and has been reported most often in patients who have been on long term oral therapy for rheumatic disorders. Acute lung injury in a patient receiving a high dose regimen for haematological malignancies has not been reported previously. We present one such case of methotrexate related acute lung injury in a patient of primary CNS lymphoma receiving high dose methotrexate. %K methotrexate %K lung in jury %K primary CNS lymphoma %U http://www.mjhid.org/article/view/9884