%0 Journal Article %T HLA PROFILE AND CLINICAL PRESENTATION OF MULTIPLE SCLEROSIS IN IRAN %A H. Kalanie %A G.R. Shamsai %J Iranian Journal of Child Neurology %D 2007 %I Iranian Child Neurology Society %X Multiple sclerosis (MS) is a demyelinating disease of the central nervous system, with unknown etiology in which both genetic and environmental factors are thought to be involved. The HLA system provides a set of genetic markers which lend themselves to systematic study. The disease also has variable clinical manifestations, ranging from a relapsing-remitting course to a chronic progressive disease. In this article we review HLA profile and clinical presentation of the disease from current available data in Iran. %K HLA %K Clinical presentation %K MS %K Iran %U http://journals.sbmu.ac.ir/ijcn/article/view/467/382