%0 Journal Article
%T Research: ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF Hedera helix LEAF EXTRACT
%A Rajesh J. Mandade*
%A Avijit Choudhuri
%A Vinod Mashirkar
%A Dinesh Sakarkar
%J Pharmacie Globale : International Journal of Comprehensive Pharmacy
%D 2010
%I 
%X The methanolic extract of the leaves of Hedera helix L. (Araliaceae) which contains mainly saponins and carbohydrate showed significant analgesic and anti-inflammatory activities (P<0.05) in the tail flick/ hot-plate test and egg albumen-induced rat paw oedema tests that were comparable to the test drugs (morphine 20mg/kg and indomethacin 50mg/kg respectively). These findings suggest that the methanol leaf extract of Hedera helix L. possess analgesic (which might have been peripherally mediated) and anti-inflammatory activities; and may lend credence to the ethnomedical claim of the use of the plant for the management of pain and inflammatory conditions.
%K Hedera helix
%K Analgesic activity
%K Anti-inflammatory activities
%K Egg albumin.
%U http://www.pharmacie-globale.info/index.php?option=com_docman&task=doc_view&gid=65&tmpl=component&format=raw&Itemid=41