%0 Journal Article
%T S¨ªndrome de Churg-Strauss: a prop¨®sito de un caso con manifestaciones poco usuales Churg-Strauss syndrome: a case with unusual manifestations
%A Mauricio Restrepo
%A Luis Alonso Gonz¨¢lez
%A Gloria V¨¢squez
%A David Londo£¿o
%J Revista Colombiana de Reumatolog¨ªa
%D 2009
%I Asociaci¨®n Colombiana de Reumatolog¨ªa
%X El s¨ªndrome de Churg-Strauss, una vasculitis sist¨¦mica necrotizante que compromete vasos de peque o y, rara vez, de mediano calibre, es junto con la granulomatosis de Wegener y la poliange¨ªtis microsc¨®pica una de las vasculitis asociadas con anticuerpos contra el citoplasma de los neutr¨®filos. Se caracteriza por asma, hipereosinofilia y granulomas extravasculares eosinof¨ªlicos. Reportamos el caso de una mujer de 36 a os con historia de asma de comienzo tard¨ªo y rinitis al¨¦rgica quien present¨® compromiso del sistema nervioso central, neuropat¨ªa perif¨¦rica, vasculitis leucocitocl¨¢stica y marcada eosinofilia. De manera interesante, esta paciente present¨® manifestaciones inusuales del s¨ªndrome de Churg-Strauss tales como microaneurismas mesent¨¦ricos y claudicaci¨®n mandibular. Adem¨¢s, presentamos una breve revisi¨®n de la literatura sobre s¨ªndrome de Churg-Strauss. Churg-Strauss syndrome, a necrotizing systemic vasculitis which involves the small and (more rarely) the medium-sized vessels, is a primary vasculitis strongly associated with antineutrophil cytoplasm antibodies (ANCA). It is characterized by the presence of asthma, eosinophilia and extravascular eosinophilic granulomas. Herein, we report a 36-year-old woman with a history of late onset asthma and allergic rhinitis who developed central nervous system involvement, peripheral neuropathy, leukocytoclastic vasculitis and eosinophilia. Interestingly, unusual clinical manifestations of Churg-Strauss syndrome such as mesenteric microaneurysms and jaw claudication were present in this particular patient. A brief review of the literature of Churg-Strauss syndrome is presented.
%K vasculitis
%K s¨ªndrome de Churg-Strauss
%K ANCA
%K microaneurismas mesent¨¦ricos
%K vasculitis
%K Churg-Strauss syndrome
%K ANCA
%K mesenteric microaneurysms
%U http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-81232009000100008