%0 Journal Article
%T Comparing Carotid Intima-Media Thickness In Type 2 Diabetes Between Patients With And Without Retinopathy
%A M Naroi Nejad
%A M Yousefi
%A H Nazari
%A A Ghasempoor
%J Tehran University Medical Journal
%D 2012
%I Tehran University of Medical Sciences
%X Background: Microangiopathy and macroangiopathy frequently coexist in type 2 diabetes mellitus (T2DM). Both types of the vascular complications share traditional risk factors but it is not clear whether the presence of microangiopathy, such as diabetic retinopathy, constitutes a predictor of atherosclerosis in carotid arteries in patients with the disease. In this study we looked for the association between diabetic retinopathy and intima-media thickness in carotid arteries of patients with T2DM. Methods: In this case-control study we examined 100 consecutive patients with T2DM in Rasoul Akram Hospital in Tehran, Iran during 2009-2010. We assessed intima-media thickness of carotid arteries by ultrasonography. All patients underwent ophthalmo-logic examination. Results: Diabetic retinopathy was found in 50 (50%) patients. Intima-media thickness was higher in patients with diabetic retinopathy than those without it (0.77¡À0.17 mm vs. 0.71¡À0.2 mm, respectively, P=0.041). Moreover, intima-media thickness was more prevalent in patients with proliferative diabetic retinopathy than patients with non-proliferative form of the disease (0.87¡À0.16 mm vs. 0.68¡À0.1 mm, respectively, P<0.001). Conclusion: Diabetic retinopathy seems to be associated with increased intima-media thickness of carotid arteries in T2DM. It may be a common denominator of pathogene-sis of microvascular complications and atherosclerosis in T2DM. Evaluations of carotid arteries are to be done by non-invasive methods such as color Doppler sonography for screening and preventing prospective cereberovascular accidents in patients with diabetic retinopathy, especially proliferative retinopathy, in routine ophthalmological examination of patients with T2DM.
%K Carotid Intima-Media Thickness
%K Diabetes
%K Retinopathy
%U http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20800.pdf&manuscript_id=20800