%0 Journal Article %T Effects of Methanolic Leaf Extract of Adansonia digitata on Serum Lipid Levels in Normal and Ethanol Fed Rats %A Matawalli A. Geidam %A Samuel A. Chabiri %A Yagana Shettima %J Pakistan Journal of Biological Sciences %D 2004 %I Asian Network for Scientific Information %X The leaf extract of Adansonia digitata is believed to contain interesting therapeutic principles, especially hypolipidaemic properties. In this study normal and ethanol fed rats were administered intragastrically by intubation 0.75 g kg 1 body weight methanolic extract of the leaves of Adansonia digitata for two weeks. The extract was found to lower the lipid levels in rats fed with alcohol and the extract and when compared to rats fed with alcohol only and those fed with no alcohol, the decrease is not significant. The possible hypolipidaemic effect could be attributed to the presence of saponins and fibre in the extract, which has been shown to bind to serum lipids especially cholesterol, thereby easing their excretion from circulation. %U http://docsdrive.com/pdfs/ansinet/pjbs/2004/1094-1095.pdf