%0 Journal Article %T A New Iridoid Glycoside from the Roots of Dipsacus asper %A De Ji %A Chunfeng Zhang %A Jingzhi Li %A Haowei Yang %A Jingyang Shen %A Zhonglin Yang %J Molecules %D 2012 %I MDPI AG %R 10.3390/molecules17021419 %X A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4¡ä,4¡ä¡ä-O-bis-¦Â-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elucidated on the basis of detailed spectroscopic analyses. Lignan is isolated from Dipsacaceae species for the first time. Compounds 1, 4 and 5 had moderate neuroprotective effects against the A¦Â25¨C35 induced cell death in PC12 cells. %K Dipsacus asper %K iridoid glycoside %K loganic acid ethyl ester %K neuroprotective effect %K Dipsaceae %U http://www.mdpi.com/1420-3049/17/2/1419