%0 Journal Article
%T Antibacterial Activity of New Dibenzoxepinone Oximes with Fluorine and Trifluoromethyl Group Substituents
%A Carmen Limban
%A Mariana Carmen Chifiriuc
%J International Journal of Molecular Sciences
%D 2011
%I MDPI AG
%R 10.3390/ijms12106432
%X In this paper we present the antimicrobial activity of some newly synthesized dibenz[ b, e]oxepin derivatives bearing the oximino moiety, and fluorine (F) and trifluoromethyl (CF 3) group substituents. The chemical structure and purity of the new compounds were assessed by using elemental analysis, NMR and FTIR spectroscopy. The new compounds were screened for their antibacterial activity towards Gram-positive and Gram-negative strains, by qualitative and quantitative assays. Our results demonstrated that the CF 3 and F disubstituted compounds could be considered for the further development of novel antimicrobial drugs.
%K dibenz[b
%K e]oxepin
%K methanone derivatives
%K antibacterial activity
%K gram-positive
%K gram-negative
%U http://www.mdpi.com/1422-0067/12/10/6432