%0 Journal Article
%T Dose-Response Relationship between Dietary Polyphenols from Acorns and Parotid Gland Hypertrophy in Pigs
%A Maria Grazia Cappai
%A Petra Wolf
%A Walter Pinna
%A Josef Kamphues
%J Food and Nutrition Sciences
%P 1261-1268
%@ 2157-9458
%D 2012
%I Scientific Research Publishing
%R 10.4236/fns.2012.39166
%X Proline contents of parotid glands (PG) in pigs constantly increase after the inclusion of different amounts of ripe hulled acorns in the diet providing high polyphenols levels. The dose-response relationship was estimated on natural hydrolizable tannins (expressed as tannic acid equivalent TAE) amounts of 25.8 to 36.1 g TAE/kg DM in experimental diets. Macroscopic and histological morphometry of parotid glands greatly varied according to feed intake and dosages of TAE ingested. The PG response (hypertrophy grade) on acorns¡¯ tannins content in the diet was positively correlated (R2 = 0.748): the response to the protein precipitating activity (PPA) of tannins consisted of a functional parotidomegaly (hypertrophy), 1.34 up to 3.55 folds than control PGs, following an oral dosage 0.596 up 1.72 TAE g¡¤kg body weight¡¤d-1 respectively, after one week exposure.
%K Acorns
%K Parotid Gland
%K Polyphenols
%K Hypertrophy
%K Proline
%K Secretory Response
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=22299