%0 Journal Article %T Informational Odds Ratio: A Useful Measure of Epidemiologic Association in Environment Exposure Studies %A Jimmy T. Efird %A Suzanne Lea %A Amanda Toland and Christopher J. Phillips %J Environmental Health Insights %D 2012 %I %R 10.4137/EHI.S9236 %X The informational odds ratio (IOR) measures the post-exposure odds divided by the pre-exposure odds (ie, information gained after knowing exposure status). A desirable property of an adjusted ratio estimate is collapsibility (ie, the combined crude ratio will not change after adjusting for a variable that is not a confounder). Adjusted traditional odds ratios (TORs) are not collapsible. In contrast, Mantel-Haenszel adjusted IORs generally are collapsible. IORs are a useful measure of disease association in environmental case-referent studies, especially when the disease is common in the exposed and/or unexposed groups. %U http://www.la-press.com/informational-odds-ratio-a-useful-measure-of-epidemiologic-association-article-a3121